Custom Peptides
Cayman Chemical AcetylLcarnItInd3chLRI 10mg
An internal standard for the quantification of L-acetylcarnitine by GC- or LC-MS
Cayman Chemical HydroxyfasudIl 10mg
An inhibitor of ROCK1 and ROCK2 (IC50s = 0.15 and 0.57 µM, respectively) and an active metabolite of HA-1077; decreases blood viscosity and prevents cerebral vasospasm in a canine model of subarachnoid hemorrhage at 3 and 10 mg/kg; reverses hypertension-associated dysfunction of NO-induced relaxation in corpus cavernosum smooth muscle in spontaneously hypertensive rats
Cayman Chemical GonadorelInacetate 10mg
A tropic hormone and agonist of GNRHR (Ki = 13 nM in CHO cells expressing the human receptor); stimulates LH and FSH release from rat anterior pituitary cultures (0.1 μg); stimulates LH release from bovine anterior pituitary cultures (1 μM); induces ovulation in rats pretreated with fluphenazine (ED50 = 610.3 ng/kg)
Cayman Chemical 2DeoxycytIdIn5OtrIphos 10mg
A nucleoside triphosphate; has commonly been used in PCR reaction mixtures as a substrate for DNA synthesis by DNA polymerases
Cayman Chemical CurcumIn nalog C1 10mg
A synthetic curcuminoid and activator of TFEB; inhibits proliferation of HCT116 cells (GI50 = 4 µM); activates TFEB, inducing nuclear translocation in Neuro2a cells at 1 µM; increases LC3-II levels and promotes autophagic flux in Neuro2a cells at 1 µM; activates TFEB and increases autophagy and lysosome biogenesis in rat brain at 10 and 25 mg/kg, p.o.
Cayman Chemical 1 2DIoleoyl3dImethylamonI 10mg
An ionizable cationic lipid (pKa = 5.59 in a TNS binding assay); has been used as a component in liposomes that can be used to encapsulate siRNA, immunostimulatory oligodeoxynucleotides, antisense oligonucleotides, or chemotherapeutic agents for in vitro and in vivo delivery
Cayman Chemical 4-hydroxy MIPT 10mg
An analytical reference standard categorized as a tryptamine; induces the HTR in mice; intended for research and forensic applications
Cayman Chemical SulfatIdebovInsodIum sa 10mg
A mixture of isolated bovine sulfatides; found in the central and peripheral nervous systems, pancreas, and immune system; primarily found in myelin; the ceramide portion contains variable fatty acid chain lengths, which are tissue- and pathology-dependent; accumulate in the lysosome of patients with metachromatic leukodystrophy
Cayman Chemical GlucosylceramIdeplnt 10mg
A mixture of glucosylceramides isolated from soy; levels decrease during cold acclimatization in plants; involved in the regulation of virulence in fungi and act as elicitors in plants, stimulating plant defense mechanisms; increased levels are associated with obesity-induced insulin resistance in mice and with neuronal deficits observed in neuronopathic Gaucher disease
Cayman Chemical PseudomonIc ACDlIthIM sal 10mg
An antibiotic; bacteriostatic against S. aureus (MIC = 0.05 UG/ml); active against skin wound clinical isolates of MRSA (MICs = 1-4 UG/ml); inhibits MRSA and P. aeruginosa biofilm formation in vitro; inhibits bacterial cell wall isoleucyl-tRNA synthetase; topical administration reduces the number of wound CFUs in a mouse model of MRSA skin infection at 2% v/v
Cayman Chemical Hbscus vtfolus Gosypn 10mg
A flavonoid glycoside with diverse biological activities; inhibits RANKL-induced osteoclastogenesis in RAW 264.7 cells at 5 µM; inhibits Aurora B kinase (IC50 = 11.07 µM in a cell-free assay), as well as Aurora A kinase and RSK2 at 20 µM; induces cell cycle arrest at the G2/M phase and apoptosis in HGC-27 cells; decreases LDH release induced by D,L-buthionine (S,R)-sulfoximine in primary rat cortical cells (IC50 = 7.4 UG/ml); reduces acetic acid-induced writhing in mice
Cayman Chemical OrforglIpron 10mg
A nonpeptide GLP-1R agonist; induces cAMP accumulation in HEK293 cells expressing human GLP-1R (EC50 = 3.05 nM); selective for GLP-1R over the GCGR, GIP receptor, and GLP-2R at 100 nM; ) prevents increases in blood glucose levels in glucose-injected mice expressing human GLP-1R but not in glucose-injected Glp1r-/- mice at 0.1, 1, or 10 mg/kg; decreases blood glucose and serum insulin levels in glucose-injected cynomolgus monkeys at 5.4 mg/kg; reduces mean food intake in cynomolgus monkeys at 0.05 or 0.1 mg/kg per day
Cayman Chemical MAM2201 N 5chloropentyl n 10mg
Differs from MAM2201 by having chlorine rather than fluorine on the terminal carbon of the alkyl group; intended for forensic and research applications
Cayman Chemical Cholyl-cadaverIn 10mg
A polyamine bile amidate; has been used as a standard for the detection of endogenous bile acid amidates in mammalian fecal samples